RESEARCH LETTER: IS THE 129S1/SVIMJ MOUSE STRAIN MORE SUITABLE TO STUDY ANTICOAGULANT-RELATED NEPHROPATHY THAN THE C57BL/6 STRAIN?

Research Letter: Is the 129S1/SvImJ Mouse Strain More Suitable to Study Anticoagulant-Related Nephropathy Than the C57BL/6 Strain?

Background: We have previously demonstrated that excessive anticoagulation with warfarin or dabigatran may result in acute kidney injury with red arcade smokey the bear belt blood cell (RBC) tubular casts in some patients with chronic kidney disease, and this condition was named anticoagulant-related nephropathy (ARN).5/6 nephrectomy (5/6NE) rats t

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C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing

Summary: The dynamic process by which nuclear RNAi engages a transcriptionally active target, before the repressive state is stably established, remains largely a mystery.Here, we found that the onset of exogenous dsRNA-induced nuclear RNAi in C.elegans is a transgenerational process, iphone 13 atlanta and it requires a putative histone methyltrans

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